Israel struck in Syria on Saturday night, targeting an area near the airport in Damascus, Syrian state media reported.
According to the report, several Israeli missiles were intercepted by Syrian air defenses.
''Our air defense systems thwarted an Israeli missile aggression," state news agency SANA cited a military source as saying.
Rami Abdurrahman, who heads the Britain-based Syrian Observatory for Human Rights, said the missile attack targeted an arms depot near the airport where new weapons recently arrived for the Iranians or Lebanon's Hezollah group.
An Israeli military spokeswoman said Israel does not comment on foreign reports.
Earlier this month, Syrian state media reported that Israeli jets attacked military targets in the northwestern Syrian city of Hama, targeting Iranian positions.