Gunmen have stormed the Save the Children office in Jalalabad killing at least five people and wounding 27 in an attack claimed by ISIS, according to the Guardian.
The latest assault on a foreign charity in Afghanistan began just after 9am when a suicide car bomb was detonated outside the office.
The attackers then used rocket-propelled grenades to blast their way inside.
Afghan security forces fought the gunmen for nearly 10 hours, at one stage rescuing nearly 50 people from the basement of the building as fighting continued on the floors above, a member of the Ningarhar provincial goverment, Sohrab Qaderi, told the Guardian.
Army officials said at least five people were killed including two soldiers, two guards working for Save the Children, and one other civilian. Another 27 were wounded, including nine Afghan security service members.
The incident was claimed by ISIS, which has established a foothold in eastern Nangarhar province. The group said in a statement it was targeting British and Swedish groups in the region.
At least four heavily armed insurgents were thought to be involved in the attack. Initial information suggested the men had been wearing military uniforms, said Attaullah Khogyani, a provincial government spokesman.
Television footage and video shot by onlookers during the attack showed thick smoke billowing from a burning car outside the complex and a fire burning on at least one floor of the building.